Lau, J., Bloch, P., Schffer, L., Pettersson, I., Spetzler, J., Kofoed, J., Madsen, K., Knudsen, L.B., McGuire, J., Steensgaard, D.B., Strauss, H.M., Gram, D.X., Knudsen, S.M., Nielsen, F.S., Thygesen, P., Reedtz-Runge, S., and Kruse, T., (2015), Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide, Journal of Medicinal Chemistry 58, 7370-7380
Inflammation affects central sensitization
Sensitivity analyses incorporated three validated pharmacovigilance methods: proportional reporting ratio (PRR), information component (IC), and empirical Bayes geometric mean (EBGM)
While this can occur with UTIs, it can also indicate other conditions that need evaluation